Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Butylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.42 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.42 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butylamine SCHEMBL11354222 | 0.97 | — | — | |
| Butylamine SCHEMBL133789 | 0.90 | — | — | |
| Butylamine SCHEMBL8633752 | 0.90 | — | — | |
| Butylamine SCHEMBL8500838 | 0.90 | — | — | |
| Monoethanolamine SCHEMBL27362457 | 0.88 | DNM1 (0.71) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Butylamine SCHEMBL3800693 | 0.88 | ALDH1A1 (0.69) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Butylamine SCHEMBL187742 | 0.87 | — | — | |
| Butylamine SCHEMBL6159373 | 0.87 | DNM1 (0.59) | DNM1ALDH1A1TSHRMEN1KMT2A | |
| Butylamine SCHEMBL25292609 | 0.87 | — | — | |
| Butylamine SCHEMBL542455 | 0.87 | DNM1 (0.73) | DNM1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106749805-B | A kind of atom transfer radical polymerization method acted on using low temperature eutectic | 华中科技大学 | 2019-07-09 | — | — | CN | claimed |