8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL28304548

Cc1ccc2cccc(O)c2n1.Oc1ccccc1-c1ccccc1O

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.82
PLAU P00749 1/20 0.50
NCF1 P14598 1/20 0.50
ALOX12 P18054 2/20 0.49
CYP1A2 P05177 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.49
HPGD P15428 1/20 0.49
CYP2C19 P33261 1/20 0.49
HIF1A Q16665 1/20 0.49
HSD17B10 Q99714 1/20 0.49
RAB9A P51151 5/20 0.48
CCR1 P32246 1/20 0.48
CCR5 P51681 1/20 0.48
PARP1 P09874 1/20 0.47
KMT2A Q03164 8/20 0.46
KDM4E B2RXH2 5/20 0.46
SOS2 Q07890 1/20 0.46
PIM1 P11309 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL29024471 0.98 METAP2 (0.79) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL29483489 0.91 METAP2 (1.00) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL297247 0.91 METAP2 (1.00) METAP2PLAUNCF1ALOX12CYP1A2
2-Phenylphenol SCHEMBL7203851 0.90 METAP2 (0.72) METAP2PLAUNCF1ALOX12CYP1A2
2-Phenylphenol SCHEMBL2439345 0.89 METAP2 (0.70) METAP2PLAUNCF1ALOX12CYP1A2
2-Phenylphenol SCHEMBL6759033 0.89 METAP2 (0.70) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL4762935 0.89 METAP2 (0.96) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL5089361 0.89 METAP2 (0.96) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL4286984 0.89 METAP2 (0.96) METAP2PLAUNCF1ALOX12CYP1A2
8-Hydroxy Quinaldine SCHEMBL4304584 0.89 METAP2 (0.96) METAP2PLAUNCF1ALOX12CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105294670-B Organic electroluminescent compounds and its organic photoelectric device 上海天马有机发光显示技术有限公司 2019-07-09 CN disclosed