Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | DAO | P14920 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 8/20 | 0.62 |
| ▸ | PDGFRA | P16234 | 8/20 | 0.62 |
| ▸ | FLT3 | P36888 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.54 |
| ▸ | XDH | P47989 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411822 | 0.88 | FLT3 (0.58) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL28414220 | 0.84 | KDM4E (0.58) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL31561461 | 0.83 | FLT3 (0.61) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL13814384 | 0.83 | PDGFRB (0.54) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL9525590 | 0.83 | PDGFRB (0.71) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL21770540 | 0.81 | KDM4E (0.67) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL29621806 | 0.81 | KDM4E (0.55) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL30509203 | 0.80 | KDM4E (0.60) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL5323920 | 0.80 | KDM4E (0.60) | KDM4EMAPTDAOHPGDSRD5A2 | |
| SCHEMBL3851187 | 0.79 | FLT3 (0.65) | KDM4EMAPTDAOHPGDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897054-A | The preparation method and its usage of triazolothiadiazole c-Met kinase inhibitor | 中国药科大学 | 2019-06-18 | — | — | CN | claimed |