Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | LMNA | P02545 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | XDH | P47989 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | DAO | P14920 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | FLT3 | P36888 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL519591 | 0.98 | KDM4E (0.69) | KDM4ELMNATP53L3MBTL1XDH | |
| SCHEMBL29493369 | 0.98 | KDM4E (0.69) | KDM4ELMNATP53L3MBTL1XDH | |
| Hydrochloric Acid SCHEMBL4591208 | 0.97 | KDM4E (0.67) | KDM4ELMNATP53L3MBTL1XDH | |
| Hydrochloric Acid SCHEMBL5159238 | 0.97 | KDM4E (0.67) | KDM4ELMNATP53L3MBTL1XDH | |
| Tetrahydrofuran SCHEMBL27478637 | 0.87 | KDM4E (0.56) | KDM4ELMNATP53L3MBTL1XDH | |
| SCHEMBL29256722 | 0.83 | XDH (0.56) | KDM4ELMNATP53L3MBTL1XDH | |
| SCHEMBL28304567 | 0.81 | KDM4E (0.64) | KDM4ELMNATP53L3MBTL1XDH | |
| SCHEMBL5957825 | 0.81 | FLT3 (0.61) | KDM4ELMNATP53L3MBTL1MAPT | |
| SCHEMBL5188980 | 0.81 | FLT3 (0.65) | KDM4ELMNATP53L3MBTL1MAPT | |
| SCHEMBL3851187 | 0.81 | FLT3 (0.65) | KDM4ELMNATP53L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | PROMEGA CORPORATION | 2020-02-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200063110-A1 | THIENOPYRROLE COMPOUNDS AND USES THEREOF | THOP1, TYMP, CREBBP | KDM4E 1930/4885LMNA 4219/4885TP53 3720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.