Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | FLT3 | P36888 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | DAO | P14920 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 7/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 7/20 | 0.50 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30509203 | 1.00 | KDM4E (0.60) | KDM4ELMNATP53L3MBTL1FLT3 | |
| SCHEMBL17440191 | 0.86 | NPC1 (0.58) | KDM4ELMNATP53L3MBTL1ALDH1A1 | |
| SCHEMBL5889520 | 0.82 | HRH3 (0.52) | KDM4ELMNAL3MBTL1FLT3HPGD | |
| SCHEMBL20764158 | 0.81 | HRH4 (0.49) | KDM4ELMNAL3MBTL1FLT3HPGD | |
| SCHEMBL28411822 | 0.81 | FLT3 (0.58) | KDM4ELMNATP53L3MBTL1FLT3 | |
| SCHEMBL30664793 | 0.80 | KDM4E (0.55) | KDM4ELMNATP53L3MBTL1FLT3 | |
| SCHEMBL5889521 | 0.80 | HRH3 (0.64) | KDM4ELMNAL3MBTL1FLT3HPGD | |
| SCHEMBL28304567 | 0.80 | KDM4E (0.64) | KDM4ELMNATP53L3MBTL1FLT3 | |
| SCHEMBL31561461 | 0.80 | FLT3 (0.61) | KDM4ELMNATP53L3MBTL1FLT3 | |
| SCHEMBL519591 | 0.79 | KDM4E (0.69) | KDM4ELMNATP53L3MBTL1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | KDM4E 4305/4885LMNA 3704/4885TP53 2946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.