Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809458 | 0.91 | LMNA (0.58) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL30157520 | 0.81 | LMNA (0.53) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL5605334 | 0.80 | POLB (0.46) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL20794724 | 0.78 | ALDH1A1 (0.61) | LMNAPKMTP53MAPK1TSHR | |
| SCHEMBL27854461 | 0.77 | ALDH1A1 (0.50) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL20794721 | 0.75 | ALDH1A1 (0.51) | LMNAPKMTP53MAPK1TSHR | |
| SCHEMBL1459903 | 0.75 | ALDH1A1 (0.62) | LMNATSHRSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL25233717 | 0.74 | LMNA (0.69) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL20153317 | 0.73 | LMNA (0.48) | LMNAPKMTP53MAPK1HSD17B10 | |
| SCHEMBL171739 | 0.73 | ALDH1A1 (0.62) | LMNAPKMTP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988092-A | The preparation method for treating the drug Nefiracetam of Alzheimer's disease | 深圳市第二人民医院 | 2019-07-09 | — | — | CN | disclosed |