Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 8/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221074 | 0.83 | TSHR (0.48) | TSHRTACR1IDO1AGXTCA1 | |
| SCHEMBL599239 | 0.82 | TSHR (0.47) | TSHRTACR1IDO1SLC6A4 | |
| SCHEMBL9565489 | 0.80 | TSHR (0.45) | TSHRTACR1CA1CA2CA7 | |
| SCHEMBL9565491 | 0.80 | TSHR (0.45) | TSHRTACR1CA1CA2CA7 | |
| SCHEMBL6555217 | 0.78 | TSHR (0.52) | TSHRTACR1IDO1AGXTSLC6A4 | |
| SCHEMBL18940105 | 0.76 | TSHR (0.54) | TSHRTACR1IDO1AGXTSLC6A4 | |
| SCHEMBL20049050 | 0.76 | TSHR (0.54) | TSHRTACR1IDO1AGXTKDM4E | |
| SCHEMBL4153126 | 0.76 | MAOA (0.55) | TSHRTACR1IDO1AGXTCA1 | |
| SCHEMBL9565513 | 0.76 | TSHR (0.48) | TSHRTACR1IDO1AGXTCA1 | |
| SCHEMBL16372159 | 0.76 | TSHR (0.48) | TSHRTACR1CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110026212-A | A kind of catalyst for cracking and the method using the catalyst preparation sitafloxacin intermediate | 临海市利民化工有限公司 | 2019-07-19 | — | — | CN | claimed |
| CN-107614501-B | Hydroxyl purine compound and application thereof | 广东众生睿创生物科技有限公司 | 2020-01-14 | — | — | CN | disclosed |
| CN-110026212-A | A kind of catalyst for cracking and the method using the catalyst preparation sitafloxacin intermediate | 临海市利民化工有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-110026212-A | A kind of catalyst for cracking and the method using the catalyst preparation sitafloxacin intermediate | 临海市利民化工有限公司 | 2019-07-19 | — | — | CN | disclosed |