Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SDHB | P21912 | 19/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | STAT3 | P40763 | 2/20 | 0.55 |
| ▸ | STAT1 | P42224 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL28875022 | 0.88 | SDHB (0.50) | SDHBLMNASTAT3STAT1RAB9A | |
| Pyridine SCHEMBL28307467 | 0.88 | SDHB (0.62) | SDHBLMNASTAT3STAT1RAB9A | |
| Pyridine SCHEMBL28874915 | 0.83 | SDHB (0.64) | SDHBLMNASTAT3STAT1RAB9A | |
| Pyridine SCHEMBL28307495 | 0.80 | SDHB (0.55) | SDHBLMNASTAT3STAT1RAB9A | |
| SCHEMBL19805653 | 0.79 | SDHB (0.68) | SDHBLMNASTAT3NPSR1TP53 | |
| SCHEMBL19805701 | 0.79 | SDHB (0.92) | SDHBLMNASTAT3STAT1RAB9A | |
| Pyridine SCHEMBL28307437 | 0.79 | SDHB (0.47) | SDHBLMNASTAT3STAT1RAB9A | |
| SCHEMBL19805817 | 0.75 | SDHB (1.00) | SDHBLMNASTAT3STAT1RAB9A | |
| SCHEMBL29975914 | 0.73 | NPSR1 (1.00) | SDHBLMNASTAT3STAT1RAB9A | |
| SCHEMBL28307436 | 0.73 | NPSR1 (1.00) | SDHBLMNASTAT3STAT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |