Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 10/20 | 1.00 |
| ▸ | SDHB | P21912 | 9/20 | 1.00 |
| ▸ | HPGD | P15428 | 9/20 | 1.00 |
| ▸ | LMNA | P02545 | 7/20 | 1.00 |
| ▸ | TP53 | P04637 | 7/20 | 1.00 |
| ▸ | STAT3 | P40763 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 6/20 | 1.00 |
| ▸ | HTT | P42858 | 6/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | STAT1 | P42224 | 4/20 | 1.00 |
| ▸ | TLR9 | Q9NR96 | 4/20 | 1.00 |
| ▸ | S1PR4 | O95977 | 4/20 | 1.00 |
| ▸ | S1PR1 | P21453 | 4/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 4/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | POLB | P06746 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29975914 | 1.00 | NPSR1 (1.00) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL4721292 | 0.88 | SDHB (0.81) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL19805665 | 0.87 | NPSR1 (1.00) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL19805673 | 0.87 | SDHB (1.00) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL19805645 | 0.86 | SDHB (1.00) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL28307444 | 0.86 | SDHB (0.75) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL29975679 | 0.86 | SDHB (0.76) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL19805664 | 0.86 | SDHB (0.76) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL3569045 | 0.86 | SDHB (0.76) | NPSR1SDHBHPGDLMNATP53 | |
| SCHEMBL19805674 | 0.86 | SDHB (1.00) | NPSR1SDHBHPGDLMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110023292-B | Apoptosis inhibitors | 北京生命科学研究所 | 2022-10-04 | — | — | CN | disclosed |
| CN-110023292-A | Apoptosis inhibitor | 北京生命科学研究所 | 2019-07-16 | — | — | CN | disclosed |