Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | SLC13A5 | Q86YT5 | 5/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374784 | 0.86 | CYP2C19 (0.57) | CYP2C19HIF1ACYP1A2TSHRCYP2D6 | |
| SCHEMBL28437734 | 0.81 | CYP2C9 (0.53) | KIF11CYP2C19HIF1ACYP1A2TSHR | |
| SCHEMBL28305537 | 0.81 | CYP2C19 (0.48) | KIF11CYP2C19HIF1ACYP1A2TSHR | |
| SCHEMBL28305527 | 0.79 | CYP2C19 (0.52) | KIF11CYP2C19HIF1ALMNAHTT | |
| SCHEMBL28874852 | 0.79 | CYP2C19 (0.56) | KIF11CYP2C19HIF1ACYP1A2SLC13A5 | |
| SCHEMBL28442638 | 0.79 | ALDH1A1 (0.50) | KIF11CYP2C19HIF1ATSHRSLC13A5 | |
| SCHEMBL28305641 | 0.79 | KCNN4 (0.51) | KIF11CYP2C19HIF1ACYP1A2 | |
| SCHEMBL28305534 | 0.78 | CYP2C19 (0.42) | CYP2C19HIF1ACYP1A2TSHRCYP2D6 | |
| SCHEMBL4016404 | 0.77 | HIF1A (0.43) | KIF11CYP2C19HIF1ACYP1A2CYP2C9 | |
| SCHEMBL28306717 | 0.75 | KCNN4 (0.51) | KIF11CYP2C19HIF1ACYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028403-A | A kind of method of synthesizing succinic acid class compound | 四川大学 | 2019-07-19 | — | — | CN | disclosed |