SCHEMBL4016404

SCHEMBL4016404

Nc1ccc(C(CC(=O)O)(C(=O)O)c2ccc(N)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.43
SLC22A8 Q8TCC7 1/20 0.43
MIF P14174 1/20 0.41
CYP2C19 P33261 3/20 0.38
CYP2C9 P11712 1/20 0.37
HPGD P15428 1/20 0.37
SLC13A5 Q86YT5 2/20 0.36
EPHX2 P34913 1/20 0.36
PTGS1 P23219 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
POLB P06746 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
MEN1 O00255 1/20 0.34
LMNA P02545 1/20 0.34
PKM P14618 1/20 0.34
APEX1 P27695 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4214180 0.82 CA2 (0.48) HIF1AMIFCYP2C19HPGDSLC13A5
SCHEMBL374784 0.81 CYP2C19 (0.57) HIF1AMAPTMIFCYP2C19SLC13A5
SCHEMBL4016674 0.81 CHEK1 (0.44) HIF1AMAPTKDM4ESLC22A6SLC22A8
SCHEMBL2220563 0.80 CYP2C19 (0.42) HIF1AMAPTMIFCYP2C19SLC13A5
SCHEMBL2388857 0.80 HIF1A (0.43) HIF1AMAPTKDM4ESLC22A6SLC22A8
SCHEMBL4246611 0.80 CYP1A2 (0.44) HIF1AMAPTKDM4ESLC22A6SLC22A8
SCHEMBL2218565 0.80 MIF (0.66) HIF1AMAPTKDM4EMIFCYP2C19
SCHEMBL30753736 0.80 KCNN4 (0.44) HIF1AMAPTMIFCYP2C19SLC13A5
SCHEMBL4025460 0.78 CHEK1 (0.39) HIF1AMAPTKDM4ESLC22A6SLC22A8
SCHEMBL1915421 0.77 ALDH1A1 (0.44) HIF1AKDM4EMIFCYP2C19SLC13A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL ASAHI KASEI KABUSHIKI KAISHA (JP) 2026-02-05 US disclosed
EP-4578892-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL Asahi Kasei Kabushiki Kaisha (JP) 2025-07-02 EP disclosed
CN-112764274-B Varnish for photo-alignment film and liquid crystal display device 株式会社日本显示器 2024-07-02 CN disclosed
WO-2024043285-A1 RESIN COMPOSITION, COMPOSITE REINFORCING MATERIAL, MOLDED BODY, AND METHOD FOR RECOVERING REINFORCING FIBERS FROM COMPOSITE REINFORCING MATERIAL 旭化成株式会社 2024-02-29 WO disclosed
US-20220315703-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2022-10-06 US disclosed
US-11456184-B2 Substrate processing method and substrate processing system TOKYO ELECTRON LIMITED (JP) 2022-09-27 US disclosed
US-11384204-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2022-07-12 US disclosed
US-20210155755-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2021-05-27 US disclosed
US-20210125837-A1 SUBSTRATE PROCESSING METHOD AND SUBSTRATE PROCESSING SYSTEM TOKYO ELECTRON LIMITED (JP) 2021-04-29 US disclosed
US-10947345-B2 Varnish for photo alignment film and liquid crystal display device JAPAN DISPLAY INC. (JP) 2021-03-16 US disclosed
US-20180022874-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2018-01-25 US disclosed
US-20170137667-A1 VARNISH FOR PHOTO ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JAPAN DISPLAY INC. (JP) 2017-05-18 US disclosed
US-9459494-B2 Liquid crystal aligning agent and liquid crystal display device employing it NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-04 US disclosed
US-9447240-B2 Polyimide precursor modified with dicarboxylic acid anhydride, imidized polyimide and liquid crystal aligning agent using it NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-09-20 US disclosed
US-20140066590-A1 POLYIMIDE PRECURSOR MODIFIED WITH DICARBOXYLIC ACID ANHYDRIDE, IMIDIZED POLYIMIDE AND LIQUID CRYSTAL ALIGNING AGENT USING IT NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2014-03-06 US disclosed
US-20140023798-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING IT NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2014-01-23 US disclosed
US-20090220707-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING IT NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2009-09-03 US disclosed
US-7498068-B2 Liquid-crystal aligning agent, liquid-crystal alignment film comprising the same, and liquid-crystal element NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-03 US disclosed
US-20070224370-A1 Liquid-Crystal Aligning Agent, Liquid-Crystal Alignment Film Comprising the Same, and Liquid-Crystal Element NISSAN CHEMICALS INDUSTRIES, LTD. (JP) 2007-09-27 US disclosed
US-20060142538-A1 Liquid crystal orientating agent and liquid crystal display element using it NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2006-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140066590-A1 POLYIMIDE PRECURSOR MODIFIED WITH DICARBOXYLIC ACID ANHYDRIDE, IMIDIZED POLYIMIDE AND LIQUID CRYSTAL ALIGNING AGENT USING IT CCDC22, RCC1, MACF1 HIF1A 832/4885MAPT 3134/4885KDM4E 1008/4885
US-20260035513-A1 RESIN COMPOSITION, REINFORCED COMPOSITE MATERIAL, SHAPED PRODUCT, AND METHOD OF RECOVERING REINFORCING FIBER FROM REINFORCED COMPOSITE MATERIAL TAF1, TAF1L, TAF9 HIF1A 721/4885MAPT 50/4885KDM4E 3188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.