Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | KDM5C | P41229 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrahydrofuran SCHEMBL28571573 | 0.84 | ALDH1A1 (0.44) | KDM4EKDM6BKDM5CEGLN1PHF8 | |
| Morpholine SCHEMBL27471707 | 0.82 | GAA (0.41) | KDM4EMGAMGAASIMGAM2 | |
| SCHEMBL285986 | 0.81 | — | — | |
| SCHEMBL28291356 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL28198858 | 0.78 | — | — | |
| SCHEMBL7163196 | 0.76 | SMN1; SMN2 (0.44) | KDM4EALDH1A1GLAPDK1PDK2 | |
| Tetrahydrofuran SCHEMBL44945 | 0.75 | — | — | |
| Tetrahydrofuran SCHEMBL1704980 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2GLASMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL28650393 | 0.75 | ALDH1A1 (0.53) | ALDH1A1LMNASLC15A2GLASMN1; SMN2 | |
| Tetrahydrofuran SCHEMBL442775 | 0.74 | ALDH1A1 (0.56) | ALDH1A1PAOXLMNASLC15A2GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104736567-B | Antibodies to aripiprazole haptens and uses thereof | 詹森药业有限公司 | 2019-09-03 | — | — | CN | disclosed |
| CN-110054694-A | The antibody and application thereof of Aripiprazole haptens | 詹森药业有限公司 | 2019-07-26 | — | — | CN | disclosed |