Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.33 |
| ▸ | WNT3A | P56704 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21758632 | 0.84 | GRM4 (0.41) | GRM4LMNAALDH1A1MEN1KMT2A | |
| Pyridine SCHEMBL21878250 | 0.81 | CLCN2 (0.39) | TDP1GRM4LMNAALDH1A1CLCN2 | |
| SCHEMBL2991016 | 0.80 | NOTUM (0.41) | LMNACLCN2P2RX7NOTUMMAPK1 | |
| SCHEMBL30524329 | 0.80 | NOTUM (0.41) | LMNACLCN2P2RX7NOTUMMAPK1 | |
| 2-Chloropyridine SCHEMBL27588435 | 0.75 | — | — | |
| 2-Chloropyridine SCHEMBL9366854 | 0.73 | — | — | |
| 2-Chloropyridine SCHEMBL16637 | 0.73 | — | — | |
| 2-Chloropyridine SCHEMBL2327116 | 0.73 | TDP1 (0.64) | TDP1KMT2ASMN1; SMN2 | |
| 2-Chloropyridine SCHEMBL10690176 | 0.73 | TDP1 (1.00) | TDP1LMNAALDH1A1MEN1KMT2A | |
| 2-Chloropyridine SCHEMBL29402311 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109912502-A | A kind of method that pyridine liquid phase Light chlorimation prepares 2,6- dichloropyridine | 浙江埃森化学有限公司 | 2019-06-21 | — | — | CN | disclosed |