SCHEMBL2991016

SCHEMBL2991016

FC(F)(F)c1ccc(Cl)c(Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 9/20 0.41
CLCN2 P51788 1/20 0.40
CYP3A4 P08684 1/20 0.40
MAPK1 P28482 1/20 0.40
P2RX7 Q99572 1/20 0.39
IDO1 P14902 2/20 0.38
HTR3E A5X5Y0 1/20 0.38
HTR3B O95264 1/20 0.38
HTR3A P46098 1/20 0.38
HTR3D Q70Z44 1/20 0.38
HTR3C Q8WXA8 1/20 0.38
KDR P35968 1/20 0.38
LMNA P02545 1/20 0.35
AHR P35869 1/20 0.34
RAPGEF4 Q8WZA2 1/20 0.34
PDK1 Q15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30524329 1.00 NOTUM (0.41) NOTUMCLCN2CYP3A4MAPK1P2RX7
Pyridine SCHEMBL21878250 0.84 CLCN2 (0.39) NOTUMCLCN2CYP3A4P2RX7KDR
SCHEMBL11264306 0.82 CYP3A4 (0.39) NOTUMCYP3A4MAPK1AHR
SCHEMBL15850524 0.82 NOTUM (0.61) NOTUMCLCN2P2RX7HTR3A
SCHEMBL1580214 0.80 NOTUM (0.39) NOTUMCLCN2P2RX7IDO1HTR3E
SCHEMBL28721260 0.80 P2RX7 (0.37) NOTUMCLCN2P2RX7
SCHEMBL3336349 0.80 NOTUM (0.39) NOTUMCLCN2CYP3A4MAPK1P2RX7
2-Chloropyridine SCHEMBL28307609 0.80 TDP1 (0.53) NOTUMCLCN2MAPK1P2RX7LMNA
SCHEMBL10493634 0.78 AR (0.40) NOTUMP2RX7IDO1HTR3EHTR3B
SCHEMBL7574925 0.78 HTR3E (0.43) NOTUMCLCN2P2RX7IDO1HTR3E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119306658-A Preparation method of chloropyridine and derivative thereof 内蒙古中辉生物科技有限公司 2025-01-14 CN claimed
CN-112174878-B Method and device for preparing 2, 6-dichloropyridine by fractional photochlorination of pyridine 浙江埃森化学有限公司 2023-05-26 CN claimed
CN-110903160-B Separation and purification method of pyridine chloride and solvent 山东埃森化学有限公司 2022-06-03 CN claimed
CN-109134355-B Method for preparing 2, 6-dichloropyridine by liquid-phase photochlorination of pyridine 浙江埃森化学有限公司 2022-04-12 CN claimed
CN-109516948-B Method and production line for preparing 2, 6-dichloropyridine by gas-phase photochlorination of pyridine 浙江埃森化学有限公司 2022-01-11 CN claimed
CN-112174878-A Method and device for preparing 2, 6-dichloropyridine by stepwise photochlorination of pyridine 浙江埃森化学有限公司 2021-01-05 CN claimed
US-10851060-B2 Method for preparing 2,6-dichloropyridine through liquid phase photochlorination of pyridine ZHEJIANG AVILIVE CHEMICAL CO., LTD. (CN) 2020-12-01 US claimed
US-20200131128-A1 METHOD FOR PREPARING 2,6-DICHLOROPYRIDINE THROUGH LIQUID PHASE PHOTOCHLORINATION OF PYRIDINE ZHEJIANG AVILIVE CHEMICAL CO., LTD. (CN) 2020-04-30 US claimed
CN-110903160-A Separation and purification method of pyridine chloride and solvent 山东埃森化学有限公司 2020-03-24 CN claimed
US-10577326-B1 Method for preparing 2-chloro-6-trichloromethylpyridine through liquid phase photochlorination of 2-methylpyridine Zhejiang Avilive Chemical, Co., Ltd. (CN) 2020-03-03 US claimed
CN-106866426-A A kind of method of comprehensive utilization of the trichlorobenzotrifluoride of accessory substance 2,4,5 for producing 3,4,5 trichlorobenzotrifluorides 浙江巍华化工有限公司 2017-06-20 CN claimed
CN-103936550-A Preparation method of 3,4,5-trichlorobenzotrifluoride JIANGSU FENGHUA CHEMICAL IND CO LTD 2014-07-23 CN claimed
US-20120154900-A1 DISPLAY DEVICES ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) 2012-06-21 US claimed
CN-101891675-B Production method of 6-chloro-2-(trichloromethyl)pyridine DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP 2011-12-14 CN claimed
CN-101891675-A Production method of 6-chloro-2-(trichloromethyl)pyridine DONGYANG YINGRUOHUA GREEN ELECTROCHEMISTRY CO LTD OF HENGDIAN GROUP 2010-11-24 CN claimed
CN-101165044-B Method for producing 2,6-dichloro-4-trifluoromethylaniline SHANGHAI HETENG FINE CHEMICALS CO LTD 2010-08-18 CN claimed
CN-101165044-A Method for producing 2,6-dichloro-4-trifluoromethylaniline SHANGHAI HETENG FINE CHEMICALS (CN) 2008-04-23 CN claimed
CN-1086374-C Process for preparing 3,4,5-trichloro-benzotrifluoride ZHEJIANG PROV CHEMICAL INST (CN) 2002-06-19 CN claimed
CN-1251359-A Process for preparing 3,4,5-trichloro-benzotrifluoride ZHEJIANG PROV CHEMICAL INST (CN) 2000-04-26 CN claimed
CN-1068106-A The new method synthetic herbicide of monoetherization oxyfluorfen SHANGHAI AGRICULTURAL CHEMICAL (CN) 1993-01-20 CN claimed