Chlorobenzene

Chlorobenzene

SCHEMBL28307653

CC#N.Clc1ccccc1.N

nearest known ligand 0.61

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
CYP1A2 P05177 1/20 0.43
LMNA P02545 4/20 0.37
CYP2A6 P11509 1/20 0.37
NPSR1 Q6W5P4 3/20 0.36
GLA P06280 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
ORAI1 Q96D31 1/20 0.36
ORAI2 Q96SN7 1/20 0.36
ORAI3 Q9BRQ5 1/20 0.36
TRPV6 Q9H1D0 1/20 0.36
SMN1; SMN2 Q16637 3/20 0.35
MAPT P10636 2/20 0.35
ADRB2 P07550 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALDH1A1 P00352 2/20 0.35
ADORA1 P30542 2/20 0.34
SQOR Q9Y6N5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL3119838 0.97 TSHR (0.65) TSHRCYP1A2LMNACYP2A6NPSR1
Chlorobenzene SCHEMBL27500933 0.97 TSHR (0.65) TSHRCYP1A2LMNACYP2A6NPSR1
Chlorobenzene SCHEMBL28416694 0.92 TSHR (0.58) TSHRCYP1A2LMNACYP2A6NPSR1
Chlorobenzene SCHEMBL10423600 0.90 TSHR (0.55) TSHRCYP1A2LMNACYP2A6NPSR1
Chlorobenzene SCHEMBL27345408 0.85
Chlorobenzene SCHEMBL27734652 0.82 TSHR (0.69) TSHRCYP1A2LMNACYP2A6NPSR1
1,4-Dichlorobenzene SCHEMBL28244272 0.82 LMNA (0.57) TSHRCYP1A2LMNACYP2A6CES2
Chlorobenzene SCHEMBL1162346 0.82
Chlorobenzene SCHEMBL1669887 0.82
Chlorobenzene SCHEMBL9840994 0.80 TSHR (0.44) TSHRCYP1A2LMNASMN1; SMN2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109912439-A Method for continuously and rapidly preparing DL-phenylglycine and analogue thereof by using cyanohydrin method 禄丰天宝磷化工有限公司 2019-06-21 CN disclosed