Chlorobenzene

Chlorobenzene

SCHEMBL9840994

C1CCOC1.CC#N.Clc1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.44
ALDH1A1 P00352 5/20 0.38
CYP1A2 P05177 2/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
LMNA P02545 3/20 0.32
CCNA2 P20248 1/20 0.32
CDK2 P24941 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.31
CRHBP P24387 2/20 0.31
CRHR2 Q13324 2/20 0.31
HTT P42858 1/20 0.31
TRPA1 O75762 1/20 0.31
TRPM8 Q7Z2W7 1/20 0.31
PHGDH O43175 1/20 0.31
HPGD P15428 1/20 0.31
MGLL Q99685 1/20 0.31
HSD17B10 Q99714 1/20 0.31
NPC1 O15118 1/20 0.31
TP53 P04637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorobenzene SCHEMBL7956389 0.87 TSHR (0.58) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL10423600 0.85 TSHR (0.55) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL18167750 0.85 TSHR (0.55) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL14685881 0.85 TSHR (0.55) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL11612566 0.85 TSHR (0.55) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL27500933 0.82 TSHR (0.65) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL3119838 0.82 TSHR (0.65) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Chlorobenzene SCHEMBL28307653 0.80 TSHR (0.61) TSHRALDH1A1CYP1A2LMNASMN1; SMN2
Toluene SCHEMBL27837594 0.80 LMNA (0.44) TSHRALDH1A1CYP1A2CYP2C9CYP2C19
Chlorobenzene SCHEMBL28416694 0.78 TSHR (0.58) TSHRALDH1A1CYP1A2LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0247366-B1 ELECTRICALLY CONDUCTING POLYMER FILM AND METHOD OF MANUFACTURING THE SAME NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1991-05-15 EP disclosed
EP-0144127-B1 ELECTRICALLY CONDUCTING POLYMER FILM AND METHOD OF MANUFACTURING THE SAME NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1990-04-04 EP disclosed
EP-0221434-B1 IMPROVING CONDUCTIVITY OF PLASTICS CONTAINING METALLIC FILLERS GENERAL ELECTRIC COMPANY (US) 1990-03-14 EP disclosed
EP-0247366-A1 Electrically conducting polymer film and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1987-12-02 EP disclosed
US-4559112-A INSULATING POLUMER FILM OF SURFACE OF ELECTRODE AROMATIC POLYMER FORMEDAT INTERFACE BETWEEN/ FILM AND ELECTRODE NIPPON TELEGRAPH & TELEPHONE (JP) 1985-12-17 US disclosed
EP-0144127-A1 Electrically conducting polymer film and method of manufacturing the same NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1985-06-12 EP disclosed