Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | MPI | P34949 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1886441 | 0.97 | ATM (0.34) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL14138100 | 0.89 | NPC1 (0.31) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL30770580 | 0.89 | STAT3 (0.41) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL8611116 | 0.85 | XIAP (0.37) | MAPK1MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL8613270 | 0.79 | ACHE (0.37) | ATMLMNANPC1MAPK1CASP3 | |
| SCHEMBL8926934 | 0.78 | CNR1 (0.33) | ATMLMNAMAPTCES2ALDH1A1 | |
| SCHEMBL14138085 | 0.77 | MAPT (0.33) | ATMLMNANPC1MAPK1RAB9A | |
| SCHEMBL30770698 | 0.73 | STAT3 (0.39) | — | |
| SCHEMBL28029389 | 0.73 | MAPT (0.48) | ATMLMNANPC1MAPK1RAB9A | |
| SCHEMBL1138203 | 0.72 | LMNA (0.60) | ATMLMNANPC1MAPK1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106332548-B | Polyurethane scorch inhibitor | 范德比尔特化学品有限责任公司 | 2019-06-14 | — | — | CN | disclosed |