Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL283117 | 0.86 | ACHE (0.42) | MMP2MMP1HDAC3HDAC1HDAC2 | |
| SCHEMBL55208 | 0.79 | MGAM (0.32) | — | |
| SCHEMBL4574096 | 0.75 | ANPEP (0.35) | MMP2HDAC3LMNAL3MBTL1HDAC8 | |
| SCHEMBL11433505 | 0.73 | ACE2 (0.46) | EPHX1 | |
| SCHEMBL10710890 | 0.71 | ACHE (0.42) | MMP2MMP1HDAC3HDAC1HDAC2 | |
| SCHEMBL10710670 | 0.70 | ALDH1A1 (0.41) | MMP2MMP1HDAC3HDAC1HDAC2 | |
| SCHEMBL10709009 | 0.69 | CA12 (0.42) | MMP2MMP1HDAC3HDAC1HDAC2 | |
| SCHEMBL22699537 | 0.68 | — | — | |
| SCHEMBL30396151 | 0.65 | — | — | |
| SCHEMBL27620783 | 0.65 | ACHE (0.45) | MMP2EPHX1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 114 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646095-B2 | Stabilised silver nanoparticles and their use | XEROX CORP (US) | 2018-10-17 | — | — | EP | disclosed |
| EP-2526098-B1 | NITROGEN-CONTAINING HETEROARYL DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2018-07-11 | — | — | EP | disclosed |
| EP-2697203-B1 | MINERALOCORTICOID RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME (US) | 2017-05-24 | — | — | EP | disclosed |
| US-9487506-B2 | Mineralocorticoid receptor antagonists | MERCK SHARP & DOHME CORP. (US) | 2016-11-08 | — | — | US | disclosed |
| EP-2440554-B1 | PYRAZOLE OXADIAZOLE DERIVATIVES AS S1P1 AGONISTS | MERCK SERONO SA (CH) | 2016-10-05 | — | — | EP | disclosed |
| EP-1696912-B1 | PYRAZOLOPYRIDINES AND ANALOGS THEREOF | 3M INNOVATIVE PROPERTIES CO (US) | 2016-05-11 | — | — | EP | disclosed |
| EP-1646095-B1 | Stabilised silver nanoparticles and their use | XEROX CORP (US) | 2016-03-09 | — | — | EP | disclosed |
| EP-2428507-B1 | Cannabinoid receptor ligands | ABBVIE BAHAMAS LTD (BS) | 2015-10-21 | — | — | EP | disclosed |
| US-9145410-B2 | Pyrazolopyridines and analogs thereof | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-09-29 | — | — | US | disclosed |
| EP-2896615-A1 | Cannabinoid receptor ligands | AbbVie Bahamas Limited (BS) | 2015-07-22 | — | — | EP | disclosed |
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | disclosed |
| US-5510320-A | EXCELLENT CONTROL OF BLACKGRASS AND WILD OATS AND OTHER WEEDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-23 | — | — | US | disclosed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | disclosed |
| EP-0610314-A1 | HERBICIDAL TRIAZOLECARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-08-17 | — | — | EP | disclosed |
| US-5334726-A | Controlling weeds | ROHM AND HAAS COMPANY (US) | 1994-08-02 | — | — | US | disclosed |
| WO-1993009100-A1 | HERBICIDAL TRIAZOLECARBOXAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| WO-1993007149-A1 | PYRAZOLOPYRIMIDINONE ANTIANGINAL AGENTS | PFIZER LIMITED (GB) | 1993-04-15 | — | — | WO | disclosed |
| US-5120347-A | Pre and postemergence | ROHM AND HAAS COMPANY (US) | 1992-06-09 | — | — | US | disclosed |
| US-4920128-A | TREATMENT OF HERPES VIRUS | STERLING DRUG INC. (US) | 1990-04-24 | — | — | US | disclosed |
| US-4206231-A | Hypoglycaemically active 2-alkyl- or -alkenyl-hydrazono propionic acid derivatives | BOEHRINGER MANNHEIM GMBH (DE) | 1980-06-03 | — | — | US | disclosed |