Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307221 | 0.81 | MAPT (0.50) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL2314528 | 0.81 | KMT2A (0.46) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL2314530 | 0.81 | KMT2A (0.46) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL28308164 | 0.79 | MAPT (0.45) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL2311394 | 0.79 | MAPT (0.53) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL28817464 | 0.75 | MAPT (0.66) | HCAR3LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL1294578 | 0.72 | MAPT (0.39) | LMNAALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL1294580 | 0.72 | MAPT (0.39) | LMNAALDH1A1MAPTKDM4ERAB9A | |
| SCHEMBL22867437 | 0.70 | GAA (0.46) | LMNAALDH1A1MAPTRAB9AGAA | |
| SCHEMBL2318048 | 0.68 | MAPT (0.47) | ALDH1A1MAPTRAB9ANPC1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957315-B | N- replaces benzenesulfonyl-azaindole oxybenzamide class compound and its prepares the purposes of drug | 中国人民解放军第二军医大学 | 2019-08-13 | — | — | CN | disclosed |