Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.49 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | BCL6 | P41182 | 1/20 | 0.45 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28307221 | 0.82 | MAPT (0.50) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28817463 | 0.80 | MAPT (0.67) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28817474 | 0.80 | MAPT (0.67) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28817471 | 0.80 | MAPT (0.67) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL8859451 | 0.80 | MAPT (0.66) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28817461 | 0.79 | MAPT (0.68) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28817467 | 0.79 | MAPT (0.64) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL864639 | 0.77 | MAPT (0.61) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL8191816 | 0.77 | MAPT (0.61) | MAPTKDM4EALDH1A1RAB9APOLB | |
| SCHEMBL28252134 | 0.76 | MAPT (0.72) | MAPTKDM4EALDH1A1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108794358-B | Substituted benzenesulfonyl compounds and application thereof in preparing medicines | 中国人民解放军第二军医大学 | 2022-08-12 | — | — | CN | disclosed |