Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | BCL6 | P41182 | 1/20 | 0.39 |
| ▸ | BCOR | Q6W2J9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28817464 | 0.82 | MAPT (0.66) | MAPTKDM4EHCAR3LMNAALDH1A1 | |
| SCHEMBL28308162 | 0.81 | HCAR3 (0.43) | MAPTKDM4EHCAR3LMNAALDH1A1 | |
| SCHEMBL28307223 | 0.80 | MAPT (0.49) | MAPTKDM4EHCAR3LMNAALDH1A1 | |
| SCHEMBL24619954 | 0.70 | HCAR3 (0.48) | MAPTHCAR3ALDH1A1KMT2APKM | |
| SCHEMBL11295495 | 0.70 | MAPT (0.56) | MAPTKDM4EHCAR3ALDH1A1MAPK1 | |
| SCHEMBL22773525 | 0.69 | FPR2 (0.44) | MAPTKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL31390954 | 0.69 | KMT2A (0.42) | MAPTKDM4EHCAR3LMNAALDH1A1 | |
| SCHEMBL11435301 | 0.67 | ALDH1A1 (0.54) | MAPTKDM4ELMNAALDH1A1MAPK1 | |
| SCHEMBL13728364 | 0.67 | KMT2A (0.47) | MAPTKDM4EHCAR3LMNAALDH1A1 | |
| SCHEMBL6966529 | 0.67 | MAPT (0.53) | MAPTKDM4ELMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106957315-B | N- replaces benzenesulfonyl-azaindole oxybenzamide class compound and its prepares the purposes of drug | 中国人民解放军第二军医大学 | 2019-08-13 | — | — | CN | disclosed |