Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14855732 | 0.98 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL29962795 | 0.95 | HPGD (0.62) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL78743 | 0.95 | HPGD (0.62) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL27873887 | 0.95 | HPGD (0.62) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| SCHEMBL28290876 | 0.93 | HPGD (0.56) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| Fluoride SCHEMBL3957036 | 0.93 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| Fluoride SCHEMBL3957041 | 0.93 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| 1,2-Dichlorobenzene SCHEMBL11313909 | 0.93 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| Selenium SCHEMBL10603347 | 0.93 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL28518250 | 0.93 | HPGD (0.60) | HPGDTSHRMAPK1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-209161893-U | Nitro-chlorobenzene produces interposition oil and separates reutilization system | 宁夏华御化工有限公司 | 2019-07-26 | — | — | CN | disclosed |