Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 4/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | POLA1 | P09884 | 2/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.32 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441998 | 0.87 | PDE3A (0.45) | ST6GAL1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL7156461 | 0.80 | LMNA (0.38) | ST6GAL1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL1525217 | 0.78 | PDE3A (0.45) | ST6GAL1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL31629449 | 0.78 | PDE4D (0.41) | ST6GAL1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL15752965 | 0.78 | EGFR (0.43) | NT5E | |
| SCHEMBL28758788 | 0.78 | PDE4D (0.42) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL4665028 | 0.77 | PDE3A (0.46) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL9868819 | 0.77 | POLA1 (0.44) | ST6GAL1PDE4DPDE3ASLC29A1LMNA | |
| SCHEMBL4586055 | 0.76 | PDE3A (0.41) | PDE4DPDE3ASLC29A1LMNATHRB | |
| SCHEMBL8716120 | 0.76 | POLA1 (0.40) | PDE4DPDE3ASLC29A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952378-A | Modified oligonucleotides and application method | 詹森生物制药有限公司 | 2019-06-28 | — | — | CN | disclosed |