Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLA1 | P09884 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL441998 | 0.89 | PDE3A (0.45) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL4586055 | 0.84 | PDE3A (0.41) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL4665028 | 0.83 | PDE3A (0.46) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL30514303 | 0.82 | LMNA (0.50) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL28758788 | 0.82 | PDE4D (0.42) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL331769 | 0.81 | LMNA (0.49) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL26666720 | 0.81 | LMNA (0.49) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL22363161 | 0.81 | POLA1 (0.42) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL9625967 | 0.81 | POLA1 (0.42) | POLA1PDE3APDE4DSLC29A1LMNA | |
| SCHEMBL1525217 | 0.80 | PDE3A (0.45) | POLA1PDE3APDE4DSLC29A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0437527-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1991-07-24 | — | — | EP | disclosed |
| WO-1990004603-A1 | NUCLEOSIDE DERIVATIVES | NYCOMED AS (NO) | 1990-05-03 | — | — | WO | disclosed |