SCHEMBL28309014

SCHEMBL28309014

Oc1c(F)cc(C(F)C(F)(F)C(F)(F)F)cc1F

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28454386 0.79 SHBG (0.45) ESR1ESR2
SCHEMBL11043796 0.78 CA1 (0.39) ESR1ESR2
SCHEMBL28316583 0.73 ESR1 (0.30) ESR1ESR2
SCHEMBL3279640 0.72 ADRB2 (0.38) ADRB2ADRB1ADRB3ESR1ESR2
SCHEMBL15727014 0.71 GLA (0.32)
SCHEMBL28641917 0.71 ESR1 (0.32) ESR1ESR2
SCHEMBL15727048 0.70
SCHEMBL320072 0.70 ESR1 (0.54) ESR1ESR2
SCHEMBL8462292 0.70 ESR1 (0.54) ESR1ESR2
SCHEMBL4471799 0.69 ADRB2 (0.39) ADRB2ADRB1ADRB3ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116845239-A Positive electrode side coating and positive electrode of lithium ion battery and lithium ion battery using same 湖北亿纬动力有限公司 2023-10-03 CN claimed
CN-113881026-B High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-12-06 CN claimed
CN-113881026-A High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-01-04 CN claimed
CN-111575824-A High-fluorine-content polyester fiber and preparation method thereof 徐毓敏 2020-08-25 CN claimed
CN-116845239-A Positive electrode side coating and positive electrode of lithium ion battery and lithium ion battery using same 湖北亿纬动力有限公司 2023-10-03 CN disclosed
CN-113881026-B High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-12-06 CN disclosed
CN-113881026-B High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-12-06 CN disclosed
CN-113881026-A High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-01-04 CN disclosed
CN-113881026-A High-fluidity liquid crystal polymer and film thereof 宁波聚嘉新材料科技有限公司 2022-01-04 CN disclosed
CN-111575824-A High-fluorine-content polyester fiber and preparation method thereof 徐毓敏 2020-08-25 CN disclosed
CN-111575824-A High-fluorine-content polyester fiber and preparation method thereof 徐毓敏 2020-08-25 CN disclosed
CN-110128837-A A kind of household electrical appliance antibiotic plastic and preparation method thereof 刘山明 2019-08-16 CN disclosed