Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7141652 | 0.83 | KMT2A (0.71) | KMT2ATSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL10811010 | 0.81 | KMT2A (0.59) | KMT2ATSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL28141075 | 0.80 | ALDH1A1 (0.55) | KDM4ELMNAALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL10502377 | 0.79 | KMT2A (1.00) | KMT2ATSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL28309027 | 0.79 | LMNA (0.62) | KMT2AKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL28141072 | 0.77 | KMT2A (0.61) | KMT2ATSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL9958465 | 0.76 | KMT2A (0.81) | KMT2ATSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL12730395 | 0.75 | KMT2A (0.78) | KMT2ATSHRKDM4ELMNAALDH1A1 | |
| SCHEMBL4734803 | 0.75 | KMT2A (0.78) | KMT2ATSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5928699 | 0.75 | KMT2A (0.78) | KMT2ATSHRKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106632092-B | A kind of 1,3- dimethyl -7- substituted quinazoline -2,4- cyclohexadione compounds and its synthetic method and application | 重庆智合生物医药有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-106632092-A | 1,3-dimethyl-7-substituted-quinazolinyl-2,4-diones, and synthesis method and application thereof | 重庆智合生物医药有限公司 | 2017-05-10 | — | — | CN | disclosed |