Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3687424 | 0.82 | HTR2C (0.65) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL3069922 | 0.81 | HTR2C (0.69) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL2538410 | 0.81 | HTR2C (0.69) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL27434393 | 0.80 | HTR2C (0.67) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL3062414 | 0.80 | HTR2C (0.67) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL29097441 | 0.78 | ALDH1A1 (0.41) | PROKR1LMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL780217 | 0.77 | SLC18A3 (0.43) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL1515269 | 0.77 | HTR2C (0.74) | HTR2CDRD2DRD1DRD4DRD5 | |
| SCHEMBL17090721 | 0.76 | KMO (0.40) | DRD2DRD3KMOHDAC4HDAC2 | |
| SCHEMBL2145468 | 0.72 | HTR2C (0.67) | HTR2CDRD2DRD1DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110105276-A | A kind of 2- quinolinone compounds and preparation method thereof | 红河学院 | 2019-08-09 | — | — | CN | disclosed |