Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | PTGES | O14684 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | APEX1 | P27695 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 5/20 | 0.48 |
| ▸ | HTR2C | P28335 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10606243 | 0.94 | HTR1A (0.52) | ALOX5PTGESPPARGAPEX1HTR1A | |
| SCHEMBL10610363 | 0.94 | HTR1A (0.52) | ALOX5PTGESPPARGAPEX1HTR1A | |
| SCHEMBL28310745 | 0.91 | HTR1A (0.50) | ALOX5PTGESPPARGHTR1AHTR2C | |
| SCHEMBL28310737 | 0.85 | HTR1A (0.53) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL10635812 | 0.82 | HTR1A (0.57) | ALOX5PTGESHTR1AKDM4EALDH1A1 | |
| SCHEMBL2931779 | 0.82 | HTR1A (0.57) | ALOX5PTGESHTR1AKDM4EALDH1A1 | |
| SCHEMBL9119119 | 0.81 | POLB (0.41) | ALOX5PTGESPPARGHTR1AHTR2C | |
| SCHEMBL9740608 | 0.81 | MEN1 (0.53) | HTR1AHTR2CKDM4EALDH1A1HPGD | |
| SCHEMBL9740606 | 0.81 | MEN1 (0.53) | HTR1AHTR2CKDM4EALDH1A1HPGD | |
| SCHEMBL9440566 | 0.80 | POLB (0.40) | ALOX5PTGESPPARGHTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105367495-B | Piperlongumine containing seven membered lactams rings is similar to object and its preparation and application | 中国人民解放军第二军医大学 | 2019-07-23 | — | — | CN | disclosed |