Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | HTR2C | P28335 | 3/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR6 | P50406 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10610363 | 1.00 | HTR1A (0.52) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL28310756 | 0.94 | ALOX5 (0.51) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL28310745 | 0.89 | HTR1A (0.50) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL10610974 | 0.83 | HTR1A (0.61) | HTR1AALOX5ALDH1A1HPGDCYP1A2 | |
| SCHEMBL29484327 | 0.83 | HTR1A (0.61) | HTR1AALOX5ALDH1A1HPGDCYP1A2 | |
| SCHEMBL10608581 | 0.83 | HTR1A (0.61) | HTR1AALOX5ALDH1A1HPGDCYP1A2 | |
| SCHEMBL28310737 | 0.83 | HTR1A (0.53) | HTR1AHTR2CHTR2ASLC6A4HTR7 | |
| SCHEMBL38662595 | 0.81 | APEX1 (0.48) | HTR1AAPEX1PPARGPTGESALOX5 | |
| SCHEMBL10611064 | 0.81 | HTR1A (0.49) | HTR1AAPEX1ALDH1A1TOP2ACYP1A2 | |
| SCHEMBL9440566 | 0.80 | POLB (0.40) | HTR1AHTR2CHTR2ASLC6A4HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0174064-B1 | COMPOSITIONS AND COMPOUNDS FOR THE TREATMENT OF PROSTATIC ADENOMA | INVERNI DELLA BEFFA S.P.A. (IT) | 1989-12-06 | — | — | EP | claimed |