Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 8/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 8/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 8/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 9/20 | 0.36 |
| ▸ | FEN1 | P39748 | 9/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27773474 | 0.79 | SCN9A (0.51) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL11076895 | 0.79 | SCN9A (0.47) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL17767985 | 0.76 | MCHR1 (0.46) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL16265343 | 0.76 | SCN9A (0.45) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL21037437 | 0.76 | — | — | |
| SCHEMBL14879888 | 0.75 | SCN9A (0.44) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL20012069 | 0.75 | SCN9A (0.44) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL17767964 | 0.75 | NUDT1 (0.44) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL14374 | 0.75 | SCN9A (0.44) | SCN9ARXRAGRIN1GRIN2BALOX5AP | |
| SCHEMBL14880376 | 0.75 | SCN9A (0.44) | SCN9ARXRAGRIN1GRIN2BALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106132963-B | (5, 6-dihydro) pyrimido [4,5-e ] indolizines | 荷兰转化研究中心有限责任公司 | 2019-08-06 | — | — | CN | disclosed |