Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenylethyl Alcohol SCHEMBL11610832 | 0.84 | TDP1 (0.84) | TDP1NPC1RAB9AMEN1KMT2A | |
| Phenylethyl Alcohol SCHEMBL27927126 | 0.82 | TDP1 (1.00) | TDP1KEAP1ALDH1A1MAPK1HDAC2 | |
| Phenylethyl Alcohol SCHEMBL28820852 | 0.82 | TDP1 (1.00) | TDP1KEAP1ALDH1A1MAPK1HDAC2 | |
| Phenylethyl Alcohol SCHEMBL8968173 | 0.82 | TDP1 (1.00) | TDP1KEAP1ALDH1A1MAPK1HDAC2 | |
| Phenylethyl Alcohol SCHEMBL1838 | 0.82 | — | — | |
| Phenylethyl Alcohol SCHEMBL1867158 | 0.82 | TDP1 (1.00) | TDP1KEAP1ALDH1A1MAPK1HDAC2 | |
| Phenylethyl Alcohol SCHEMBL11450063 | 0.82 | TDP1 (1.00) | TDP1KEAP1ALDH1A1MAPK1HDAC2 | |
| SCHEMBL1371070 | 0.81 | KEAP1 (0.61) | TDP1NPC1RAB9AMEN1KMT2A | |
| Phenylethyl Alcohol SCHEMBL28312218 | 0.81 | TDP1 (0.70) | TDP1NPC1RAB9AMEN1KMT2A | |
| Phenylethyl Alcohol SCHEMBL183529 | 0.80 | TDP1 (0.76) | TDP1KEAP1ALDH1A1MAPK1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110191949-A | Recombinant virus, the composition comprising the recombinant virus with and application thereof | 中央研究院 | 2019-08-30 | — | — | CN | disclosed |