Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK7 | P50613 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | CCNH | P51946 | 2/20 | 0.44 |
| ▸ | MNAT1 | P51948 | 2/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 8/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | IGF1R | P08069 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | FLT4 | P35916 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29509186 | 0.87 | DGAT1 (0.43) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL21178225 | 0.87 | DGAT1 (0.43) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL21184412 | 0.85 | DGAT1 (0.38) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL29492508 | 0.83 | DGAT1 (0.38) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL25597470 | 0.83 | DGAT1 (0.38) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL25421692 | 0.82 | DGAT1 (0.38) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL30976735 | 0.82 | BUB1 (0.36) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL30439371 | 0.82 | CDK7 (0.43) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL25258483 | 0.82 | CDK7 (0.43) | CCNT1CDK7CDK9CCNHMNAT1 | |
| SCHEMBL21184629 | 0.81 | DGAT1 (0.43) | CCNT1CDK7CDK9CCNHMNAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110036004-A | Inhibitors of cyclin dependent kinase 7(CDK7) | 希洛斯医药品股份有限公司 | 2019-07-19 | — | — | CN | disclosed |