Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875477 | 0.76 | POLB (0.40) | POLBGBA1 | |
| SCHEMBL18883041 | 0.74 | NOS1 (0.42) | POLBGBA1 | |
| SCHEMBL18883042 | 0.74 | NOS1 (0.42) | POLBGBA1 | |
| SCHEMBL18883048 | 0.74 | NOS1 (0.42) | POLBGBA1 | |
| SCHEMBL18883040 | 0.74 | NOS1 (0.42) | POLBGBA1 | |
| SCHEMBL23255522 | 0.74 | NOS1 (0.42) | POLBGBA1 | |
| SCHEMBL23477650 | 0.72 | POLB (0.47) | POLBGBA1 | |
| SCHEMBL23477733 | 0.72 | POLB (0.47) | POLBGBA1 | |
| SCHEMBL13953752 | 0.72 | POLB (0.47) | POLBGBA1 | |
| SCHEMBL23459137 | 0.72 | POLB (0.47) | POLBGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139929-A | Bacterial glutaminyl cyclase and inhibitors thereof for the treatment of periodontitis | 德国弗劳恩霍夫应用研究促进协会 | 2019-08-16 | — | — | CN | disclosed |