Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312585 | 0.82 | P2RX7 (0.33) | GBA1MEN1KMT2A | |
| SCHEMBL15250705 | 0.77 | GBA1 (0.50) | GBA1MEN1KMT2A | |
| SCHEMBL23951733 | 0.77 | GBA1 (0.50) | GBA1MEN1KMT2A | |
| SCHEMBL5521949 | 0.77 | GBA1 (0.50) | GBA1MEN1KMT2A | |
| SCHEMBL2098491 | 0.77 | GBA1 (0.50) | GBA1MEN1KMT2A | |
| SCHEMBL27979655 | 0.76 | MEN1 (0.42) | GBA1MEN1KMT2A | |
| SCHEMBL28312583 | 0.76 | POLB (0.41) | POLBGBA1 | |
| SCHEMBL4390333 | 0.75 | ALDH1A1 (0.40) | POLB | |
| SCHEMBL23951730 | 0.68 | MEN1 (0.42) | GBA1MEN1KMT2A | |
| SCHEMBL4023292 | 0.68 | GLB1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110139929-A | Bacterial glutaminyl cyclase and inhibitors thereof for the treatment of periodontitis | 德国弗劳恩霍夫应用研究促进协会 | 2019-08-16 | — | — | CN | disclosed |