Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2828927 | 0.94 | HTR1A (0.32) | THRBTHRAHTR1ANR1I2CYP3A4 | |
| SCHEMBL2832943 | 0.90 | HTR1A (0.32) | HTR1ANR1I2CYP3A4CYP2D6 | |
| SCHEMBL2829232 | 0.89 | S1PR1 (0.34) | THRBTHRAALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL2836130 | 0.89 | S1PR2 (0.36) | THRBTHRAALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL2836196 | 0.88 | TP53 (0.34) | THRBTHRAALDH1A1HTR1AMAPT | |
| SCHEMBL2833161 | 0.85 | — | — | |
| SCHEMBL2830481 | 0.84 | S1PR2 (0.34) | HTR1AS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL2831013 | 0.84 | HTR1A (0.33) | HTR1AS1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL2830263 | 0.84 | SRD5A2 (0.33) | — | |
| SCHEMBL2832504 | 0.83 | CYP3A4 (0.36) | CYP3A4CYP2D6NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160555-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2133380-A1 | RESIN COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2009-12-16 | — | — | EP | disclosed |