Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.32 |
| ▸ | THRA | P10827 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2831013 | 0.95 | HTR1A (0.33) | S1PR1S1PR3S1PR2LPAR2HTR1A | |
| SCHEMBL2836130 | 0.92 | S1PR2 (0.36) | S1PR1S1PR3S1PR2LPAR2HTR1A | |
| SCHEMBL2831164 | 0.91 | HTR1A (0.33) | S1PR1S1PR3S1PR2LPAR2HTR1A | |
| SCHEMBL2831311 | 0.89 | THRB (0.33) | S1PR1S1PR3S1PR2LPAR2HTR1A | |
| SCHEMBL2830481 | 0.87 | S1PR2 (0.34) | S1PR1S1PR3S1PR2LPAR2HTR1A | |
| SCHEMBL2836196 | 0.86 | TP53 (0.34) | HTR1ATHRBTHRAALDH1A1 | |
| SCHEMBL2831101 | 0.86 | THRA (0.32) | THRBTHRA | |
| SCHEMBL2831041 | 0.85 | GLRA1 (0.32) | — | |
| SCHEMBL2828927 | 0.84 | HTR1A (0.32) | HTR1ATHRBTHRA | |
| SCHEMBL2829781 | 0.84 | CYP3A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100160555-A1 | RESIN COMPOSITION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-24 | — | — | US | disclosed |
| EP-2133380-A1 | RESIN COMPOSITION | Sumitomo Chemical Company, Limited (JP) | 2009-12-16 | — | — | EP | disclosed |