SCHEMBL28313147

SCHEMBL28313147

CCC/C(=C/C(=O)O)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 4/20 0.40
HDAC1 Q13547 4/20 0.40
HDAC2 Q92769 4/20 0.40
HDAC8 Q9BY41 4/20 0.40
FFAR3 O14843 3/20 0.40
KDM4E B2RXH2 2/20 0.38
TSHR P16473 2/20 0.38
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
CTSD P07339 1/20 0.34
FAAH O00519 3/20 0.33
ATM Q13315 1/20 0.33
MEN1 O00255 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C19 P33261 1/20 0.32
SOAT1 P35610 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL377345 1.00 HDAC3 (0.40) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL5176301 0.87 CES1 (0.41) TSHRCES2CES1FAAHMEN1
SCHEMBL5176308 0.87 CES1 (0.41) TSHRCES2CES1FAAHMEN1
SCHEMBL5177367 0.87 CES1 (0.41) TSHRCES2CES1FAAHMEN1
SCHEMBL7666343 0.84 POLB (0.38) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL5285157 0.84 POLB (0.38) HDAC3HDAC1HDAC2HDAC8FFAR3
SCHEMBL28283297 0.84 FAAH (0.49) TSHRCES2CES1FAAHMEN1
SCHEMBL28054391 0.84 FAAH (0.49) TSHRCES2CES1FAAHMEN1
SCHEMBL27564543 0.84 FAAH (0.49) TSHRCES2CES1FAAHMEN1
SCHEMBL28196445 0.84 FAAH (0.49) TSHRCES2CES1FAAHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106803590-B A kind of lithium ion battery negative material bonding agent and negative electrode material and lithium battery 德阳九鼎智远知识产权运营有限公司 2019-08-02 CN disclosed