SCHEMBL5285157

SCHEMBL5285157

CCCC(=CC(N)=O)C(N)=O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HDAC3 O15379 4/20 0.36
HDAC1 Q13547 4/20 0.36
HDAC2 Q92769 4/20 0.36
HDAC8 Q9BY41 4/20 0.36
FFAR3 O14843 3/20 0.36
CTSD P07339 1/20 0.36
TSHR P16473 1/20 0.35
FAAH O00519 3/20 0.34
SOAT1 P35610 2/20 0.33
ALDH1A1 P00352 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
HDAC6 Q9UBN7 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7666343 1.00 POLB (0.38) POLBCES2CES1HDAC3HDAC1
Ammonia Solution, Strong SCHEMBL2389746 0.98 POLB (0.36) POLBCES2CES1HDAC3HDAC1
SCHEMBL381319 0.86 CES1 (0.42) POLBCES2CES1FAAHSOAT1
SCHEMBL28203317 0.86 CES1 (0.42) POLBCES2CES1FAAHSOAT1
SCHEMBL381320 0.86 CES1 (0.42) POLBCES2CES1FAAHSOAT1
SCHEMBL3677658 0.84 FFAR3 (0.40) POLBCES2CES1HDAC3HDAC1
SCHEMBL28313147 0.84 HDAC3 (0.40) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL3677661 0.84 FFAR3 (0.40) POLBCES2CES1HDAC3HDAC1
SCHEMBL377345 0.84 HDAC3 (0.40) CES2CES1HDAC3HDAC1HDAC2
SCHEMBL7564416 0.83 FAAH (0.50) CES2CES1TSHRFAAHSOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106749962-B A kind of highly resistance chamotte mould polycarboxylate water-reducer and preparation method thereof 浙江建研科之杰新材料有限公司 2019-01-08 CN claimed
CN-100344654-C Method for preparing water soluble polymer material CHANGCHUN APPLIED CHEMISTRY (CN) 2007-10-24 CN claimed
CN-1709924-A Method for preparing water soluble polymer material CHANGCHUN APPLIED CHEMISTRY (CN) 2005-12-21 CN claimed
CN-104736516-B Sodium p-styrenesulfonate, process for producing the same, sodium p-styrenesulfonate, dispersant using the same, and synthetic paste for dressing 东曹精细化工株式会社 2019-11-08 CN disclosed
CN-109294314-A A kind of epoxy acrylic cathode electrophoresis dope resin emulsion and preparation method thereof 中国海洋石油集团有限公司 2019-02-01 CN disclosed
CN-109071960-A Silicon-containing heterocyclic compound and matting agent 富士胶片和光纯药株式会社 2018-12-21 CN disclosed
CN-106543356-B A kind of hydrogel sheath and preparation method thereof 华中科技大学 2018-11-30 CN disclosed
CN-106543356-A A kind of hydrogel sheath and preparation method thereof 华中科技大学 2017-03-29 CN disclosed
EP-1281516-B1 Planographic printing plate precursor FUJIFILM CORP (JP) 2007-12-19 EP disclosed
CN-100344654-C Method for preparing water soluble polymer material CHANGCHUN APPLIED CHEMISTRY (CN) 2007-10-24 CN disclosed
CN-1709924-A Method for preparing water soluble polymer material CHANGCHUN APPLIED CHEMISTRY (CN) 2005-12-21 CN disclosed
US-6951171-B2 Using graft polymer on etched or anodized aluminum substrate FUJI PHOTO FILM CO., LTD. (JP) 2005-10-04 US disclosed
US-20030129520-A1 Using graft polymer on etched or anodized aluminum substrate FUJIFILM CORPORATION (JP) 2003-07-10 US disclosed
EP-1281516-A2 Planographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2003-02-05 EP disclosed
US-6414013-B1 KINASE INHIBITORS; ANTICANCER AGENTS PHARMACIA & UPJOHN S.P.A. (IT) 2002-07-02 US disclosed