Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TFEB | P19484 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | ACR | P10323 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29999157 | 0.98 | THRA (0.53) | THRATHRBCA12CA1CA2 | |
| SCHEMBL2235806 | 0.98 | THRA (0.53) | THRATHRBCA12CA1CA2 | |
| Acrylic Acid SCHEMBL28864008 | 0.93 | THRA (0.49) | THRATHRBCA12CA1CA2 | |
| SCHEMBL3841280 | 0.88 | THRB (0.56) | THRATHRBSMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL29413361 | 0.88 | THRB (0.56) | THRATHRBSMN1; SMN2KMT2AALDH1A1 | |
| 1,2-Dimethoxybenzene SCHEMBL27708878 | 0.85 | CA12 (0.52) | CA12CA1CA2CA4CA7 | |
| SCHEMBL5604717 | 0.83 | THRB (0.53) | THRATHRBALDH1A1LMNATDP1 | |
| SCHEMBL9284213 | 0.82 | MAPT (0.58) | CA12CA1CA2CA4CA7 | |
| SCHEMBL14173222 | 0.82 | THRB (0.51) | THRATHRBSMN1; SMN2KMT2AHTT | |
| SCHEMBL30226804 | 0.82 | TYMS (0.50) | THRATHRBSMN1; SMN2KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156733-A | A kind of tyrosinase inhibitor and its application | 润和生物医药科技(汕头)有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-110156733-A | A kind of tyrosinase inhibitor and its application | 润和生物医药科技(汕头)有限公司 | 2019-08-23 | — | — | CN | disclosed |