Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL1311380 | 0.84 | TGM2 (0.55) | TGM2THRBATMCA1CA2 | |
| Mequinol SCHEMBL1260964 | 0.82 | ESR2 (0.57) | TGM2THRBATMCA1CA2 | |
| Anisole SCHEMBL7290982 | 0.82 | CA4 (0.61) | TGM2THRBATMCA1CA2 | |
| Acrylic Acid SCHEMBL28864006 | 0.81 | THRB (0.54) | TGM2THRBATMCA1CA2 | |
| Acrylic Acid SCHEMBL28304090 | 0.81 | TGM2 (0.51) | TGM2THRBATMCA1CA2 | |
| Anisole SCHEMBL28780062 | 0.80 | CA4 (0.58) | TGM2THRBATMCA1CA2 | |
| SCHEMBL4747628 | 0.78 | — | — | |
| 4-Methoxycinnamic Acid SCHEMBL2468607 | 0.77 | THRB (0.86) | THRBATMALDH1A1MAPTF3 | |
| Anisole SCHEMBL28850433 | 0.76 | CA4 (0.52) | TGM2THRBATMCA1CA2 | |
| Boric Acid SCHEMBL29098230 | 0.74 | CA1 (0.56) | THRBCA1CA2CES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156733-A | A kind of tyrosinase inhibitor and its application | 润和生物医药科技(汕头)有限公司 | 2019-08-23 | — | — | CN | claimed |
| CN-110156733-A | A kind of tyrosinase inhibitor and its application | 润和生物医药科技(汕头)有限公司 | 2019-08-23 | — | — | CN | disclosed |