Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HTR2C | P28335 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.56 |
| ▸ | HTR1B | P28222 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | HTR6 | P50406 | 1/20 | 0.56 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4404041 | 0.81 | HTR2A (0.61) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL4985934 | 0.78 | HTR2A (0.77) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL13668031 | 0.78 | HTR2A (0.61) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL5598639 | 0.78 | HTR2A (0.61) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL12949464 | 0.77 | HTR2A (0.56) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL5513682 | 0.75 | HTR2A (0.67) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL14270220 | 0.75 | HTR2A (0.57) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL20038789 | 0.75 | ALDH1A1 (0.57) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL31201415 | 0.75 | HTR2A (0.57) | HTR2ACYP3A4HTR2CCYP1A2MPO | |
| SCHEMBL5513944 | 0.75 | MAPT (0.57) | HTR2ACYP3A4HTR2CCYP1A2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107445969-B | A kind of tricyclic indole derivatives and its preparation and application | 福州大学 | 2019-07-09 | — | — | CN | disclosed |