Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HTR6 | P50406 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | MPO | P05164 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.61 |
| ▸ | HTR1B | P28222 | 1/20 | 0.61 |
| ▸ | HTR7 | P34969 | 1/20 | 0.61 |
| ▸ | CTSK | P43235 | 1/20 | 0.61 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | AHR | P35869 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985934 | 0.82 | HTR2A (0.77) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL5598639 | 0.82 | HTR2A (0.61) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL13668031 | 0.82 | HTR2A (0.61) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL28313348 | 0.81 | HTR2A (0.56) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL12949464 | 0.81 | HTR2A (0.56) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL5513682 | 0.79 | HTR2A (0.67) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL14270220 | 0.79 | HTR2A (0.57) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL31201415 | 0.79 | HTR2A (0.57) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL5513944 | 0.79 | MAPT (0.57) | HTR2ACYP3A4HTR2CHTR6CYP1A2 | |
| SCHEMBL21377613 | 0.79 | HTR2A (0.53) | HTR2ACYP3A4HTR2CHTR6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615638-B2 | Synthesis of grossularines-1 and analogs thereof and method of use | CITY OF HOPE (US) | 2009-11-10 | — | — | US | claimed |
| US-20080033004-A1 | SYNTHESIS OF GROSSULARINES-1 AND ANALOGS THEREOF AND METHOD OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-07 | — | — | US | claimed |
| CN-122079853-A | N-substituted indoles and other heterocyclic compounds for the treatment of brain diseases | — | 2026-05-26 | — | — | CN | disclosed |
| CN-113786407-B | Organic compound | 细胞内治疗公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20200345727-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2020-11-05 | — | — | US | disclosed |
| WO-2016023106-A1 | BIS-INDOLE ALKALOIDS FOR USE IN THE TREATMENT OF INFECTIONS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-02-18 | — | — | WO | disclosed |
| US-7615638-B2 | Synthesis of grossularines-1 and analogs thereof and method of use | CITY OF HOPE (US) | 2009-11-10 | — | — | US | disclosed |
| US-7615638-B2 | Synthesis of grossularines-1 and analogs thereof and method of use | CITY OF HOPE (US) | 2009-11-10 | — | — | US | disclosed |
| US-20080033004-A1 | SYNTHESIS OF GROSSULARINES-1 AND ANALOGS THEREOF AND METHOD OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-07 | — | — | US | disclosed |
| US-20080033004-A1 | SYNTHESIS OF GROSSULARINES-1 AND ANALOGS THEREOF AND METHOD OF USE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-02-07 | — | — | US | disclosed |
| EP-1653948-A2 | USE OF 5-METHOXYTRYPTAMINE AS A CARDIOPROTECTIVE AGENT | Dabur Research Foundation (IN) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005009419-A2 | USE OF 5-METHOXYTRYPTAMINE AS A CARDIOPROTECTIVE AGENTS | DABUR RESEARCH FOUNDATION (IN) | 2005-02-03 | — | — | WO | disclosed |
| US-6841685-B2 | Methods for making bis-heterocyclic alkaloids | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2005-01-11 | — | — | US | disclosed |
| US-20030232988-A1 | Methods for making bis-heterocyclic alkaloids | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY,THE | 2003-12-18 | — | — | US | disclosed |
| EP-1089723-A4 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX INC (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2001094310-A1 | METHODS FOR MAKING BIS-HETEROCYCLIC ALKALOIDS | THE STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2001-12-13 | — | — | WO | disclosed |
| EP-1089723-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | Medinox, Inc. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999066918-A1 | THERAPEUTIC METHODS EMPLOYING DISULFIDE DERIVATIVES OF DITHIOCARBAMATES AND COMPOSITIONS USEFUL THEREFOR | MEDINOX, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030232988-A1 | Methods for making bis-heterocyclic alkaloids | CIAPIN1, AAAS, MDN1 | HTR2A 2569/4885CYP3A4 3322/4885HTR2C 1903/4885 |
| US-20080033004-A1 | SYNTHESIS OF GROSSULARINES-1 AND ANALOGS THEREOF AND METHOD OF USE | INMT, GNMT, HTR5A | HTR2A 34/4885CYP3A4 454/4885HTR2C 6/4885 |
| US-20200345727-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | HTR2A 1445/4885CYP3A4 3526/4885HTR2C 1925/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.