Propene

Propene

SCHEMBL28313374

C=CC.CCCCCN1CNCNC1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GNAO1 P09471 8/20 0.38
GNAI3 P08754 7/20 0.38
GNAI1 P63096 7/20 0.38
GUSB P08236 2/20 0.35
EBP Q15125 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.31
SOD3 P08294 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20418301 0.90 GNAO1 (0.43) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL3313743 0.88 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL8751413 0.88 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL3310643 0.88 GNAO1 (0.46) GNAO1GNAI3GNAI1GUSBEBP
Hydrochloric Acid SCHEMBL27558043 0.84 GNAO1 (0.43) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL6557162 0.83 GLB1 (0.40) GNAO1GNAI3GNAI1GUSBEBP
SCHEMBL27558042 0.81 GNAO1 (0.41) GNAO1GNAI3GNAI1GUSBEBP
Propene SCHEMBL28191652 0.77 GNAI3 (0.57) GNAO1GNAI3GNAI1EBPSIGMAR1
Propene SCHEMBL28189504 0.77 GNAO1 (0.53) GNAO1GNAI3GNAI1SIGMAR1SOD3
SCHEMBL11681717 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110099961-A Polycarbonate compositions with good mechanical performance 科思创德国股份有限公司 2019-08-06 CN disclosed