Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 6/20 | 0.80 |
| ▸ | MARS1 | P56192 | 4/20 | 0.62 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.54 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.54 |
| ▸ | MCTS1 | Q9ULC4 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27706390 | 0.79 | MAPT (0.56) | MALT1MARS1MEN1KMT2AMME | |
| SCHEMBL117498 | 0.77 | MARS1 (1.00) | MALT1MARS1 | |
| SCHEMBL27851807 | 0.76 | MALT1 (0.49) | MALT1MARS1MEN1KMT2A | |
| SCHEMBL4429627 | 0.74 | MALT1 (0.55) | MALT1MARS1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL15579547 | 0.74 | MALT1 (0.55) | MALT1MARS1MEN1KMT2ASMPD1 | |
| SCHEMBL18300791 | 0.73 | SLC16A3 (0.61) | MALT1MARS1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL29819771 | 0.73 | SLC16A3 (0.61) | MALT1MARS1SLC16A3SLC16A1MCTS1 | |
| SCHEMBL976287 | 0.72 | MALT1 (0.56) | MALT1MARS1MEN1KMT2ASMPD1 | |
| SCHEMBL2552942 | 0.72 | GRM5 (0.61) | MALT1MEN1KMT2ASMPD1MME | |
| SCHEMBL25410771 | 0.72 | MARS1 (0.62) | MALT1MARS1SLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156708-A | A kind of compound substitution heterocycle class and its preparation method and application containing acylhydrazone skeleton | 中国药科大学 | 2019-08-23 | — | — | CN | disclosed |