Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | MARS1 | P56192 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATP4A | P20648 | 1/20 | 0.39 |
| ▸ | ATP4B | P51164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27831427 | 0.90 | MARS1 (0.53) | MALT1SIRT2NT5EBRD4MARS1 | |
| SCHEMBL27833746 | 0.81 | SIRT2 (0.46) | SIRT2NT5EBRD4PTGDR2ALDH1A1 | |
| SCHEMBL28791613 | 0.78 | SIRT2 (0.44) | SIRT2NT5EPTGDR2ALDH1A1HTT | |
| SCHEMBL27811119 | 0.77 | BRD4 (0.52) | BRD4MARS1ALDH1A1TDO2HTT | |
| SCHEMBL28313528 | 0.76 | MALT1 (0.80) | MALT1MARS1KMT2AMEN1 | |
| SCHEMBL27811236 | 0.74 | MAPT (0.51) | BRD4ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL27831429 | 0.74 | GRN (0.49) | SIRT2NT5EBRD4MARS1ALDH1A1 | |
| SCHEMBL28791272 | 0.73 | SMPD1 (0.48) | SIRT2BRD4MAPT | |
| SCHEMBL27897837 | 0.72 | GHSR (0.42) | PTGDR2ALDH1A1HTTMAPTKMT2A | |
| SCHEMBL27831436 | 0.71 | MAPT (0.47) | ALDH1A1HTTMAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | claimed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | claimed |
| CN-102321074-B | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2013-04-10 | — | — | CN | disclosed |
| CN-102321074-A | Indole ring-substituted pyrazole hydrazide derivative and preparation method and application thereof | SHANDONG INST LIGHT INDUSTRY | 2012-01-18 | — | — | CN | disclosed |