SCHEMBL28313790

SCHEMBL28313790

CCCCC(Cl)S(=O)(=O)Cl

nearest known ligand 0.36

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.36
TP53 P04637 1/20 0.35
DNM1 Q05193 2/20 0.35
TSHR P16473 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
FDPS P14324 1/20 0.34
MAPK1 P28482 1/20 0.33
CA1 P00915 2/20 0.32
CA12 O43570 1/20 0.32
CA7 P43166 1/20 0.32
CA14 Q9ULX7 1/20 0.32
LCK P06239 1/20 0.31
PPARD Q03181 1/20 0.31
ZDHHC20 Q5W0Z9 1/20 0.31
ZDHHC2 Q9UIJ5 1/20 0.31
ALDH1A1 P00352 2/20 0.31
FAAH O00519 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6363952 0.91 CA2 (0.42) CA2TP53DNM1FDPSLCK
SCHEMBL5804587 0.84
SCHEMBL9481755 0.82 CA2 (0.38) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL6208470 0.80 CA2 (0.36) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL9170810 0.80 CA2 (0.36) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL8521185 0.78 TP53 (0.43) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL1692881 0.78 CA2 (0.48) CA2TP53CA1CA12CA7
SCHEMBL5888772 0.77 TP53 (0.37) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL27289489 0.77 TP53 (0.37) CA2TP53DNM1TSHRSMN1; SMN2
SCHEMBL17710323 0.76 CA2 (0.38) CA2TP53DNM1TSHRSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110167530-A Nanoparticle-based liver-targeted therapy MIDA科技有限公司 2019-08-23 CN disclosed