Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9481755 | 0.82 | CA2 (0.38) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL9170810 | 0.80 | CA2 (0.36) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL28313790 | 0.80 | CA2 (0.36) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL8521185 | 0.78 | TP53 (0.43) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL1692881 | 0.78 | CA2 (0.48) | CA2TP53CA1CA12CA7 | |
| SCHEMBL17710323 | 0.76 | CA2 (0.38) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL27077587 | 0.73 | — | — | |
| SCHEMBL181188 | 0.73 | — | — | |
| SCHEMBL14892606 | 0.72 | TP53 (0.37) | CA2TP53DNM1TSHRSMN1; SMN2 | |
| SCHEMBL5637608 | 0.72 | TP53 (0.46) | CA2TP53DNM1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103193840-A | Macrolide derivative | TAISHO PHARMACEUTICAL CO LTD | 2013-07-10 | — | — | CN | disclosed |
| CN-101454334-B | Macrolide derivatives | TAISHO PHARMACEUTICAL CO LTD | 2013-04-10 | — | — | CN | disclosed |
| CN-101454334-A | Macrolide derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2009-06-10 | — | — | CN | disclosed |
| CN-1275964-C | 7-oxo pyridopyrimidines as inhibitors of a cellular proliferation | HOFFMANN LA ROCHE (CH) | 2006-09-20 | — | — | CN | disclosed |
| EP-1549632-A4 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | DIMENSIONAL PHARM INC (US) | 2005-11-09 | — | — | EP | disclosed |
| EP-1549632-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2005-07-06 | — | — | EP | disclosed |
| WO-2003099805-A1 | NOVEL THIOPHENE AMIDINES, COMPOSITIONS THEREOF, AND METHODS OF TREATING COMPLEMENT-MEDIATED DISEASES AND CONDITIONS | 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) | 2003-12-04 | — | — | WO | disclosed |
| CN-1451005-A | 7-oxopyridopyrimidines as inhibitors of cell proliferation | HOFFMANN LA ROCHE (CH) | 2003-10-22 | — | — | CN | disclosed |
| CN-1058780-A | Has the active thiazolidine carboxylic acid amides derivative of anti-allergy, their preparation and application | SANKYO CO (JP) | 1992-02-19 | — | — | CN | disclosed |