Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28313812

CC(C)C(NC(=O)OC(C)(C)C)C(=O)O.N

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CTSK P43235 4/20 0.59
CTSS P25774 3/20 0.59
CA2 P00918 2/20 0.51
CA1 P00915 1/20 0.51
CA7 P43166 1/20 0.51
PREP P48147 1/20 0.48
TRPA1 O75762 2/20 0.47
CTSL P07711 2/20 0.47
CTSB P07858 2/20 0.47
CYP2D6 P10635 1/20 0.46
TSHR P16473 2/20 0.44
APP P05067 1/20 0.43
KMT2A Q03164 2/20 0.43
SDCBP O00560 1/20 0.43
SDC2 P34741 1/20 0.43
MEN1 O00255 1/20 0.42
GAA P10253 1/20 0.42
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL256794 0.98 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL467994 0.98 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL59323 0.98 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL29674710 0.98 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL28058549 0.96 CTSK (0.59) CTSKCTSSCA2CA1CA7
Fluoride SCHEMBL7360444 0.96 CTSK (0.59) CTSKCTSSCA2CA1CA7
Fluoride SCHEMBL7360449 0.96 CTSK (0.59) CTSKCTSSCA2CA1CA7
SCHEMBL22371979 0.91 CTSK (0.63) CTSKCTSSCA2CA1CA7
SCHEMBL7345607 0.91 CTSK (0.63) CTSKCTSSCA2CA1CA7
SCHEMBL22371977 0.91 CTSK (0.63) CTSKCTSSCA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110054603-B Synthetic method of aryl carbon glycoside compound 南开大学 2020-12-01 CN claimed
CN-110054603-A A kind of synthetic method of aryl c-glycosides 南开大学 2019-07-26 CN claimed
CN-110054603-A A kind of synthetic method of aryl c-glycosides 南开大学 2019-07-26 CN disclosed