Sugi Predict

Sugi Predict / Compounds / SCHEMBL256794

SCHEMBL256794

SCHEMBL256794

CC(C)[C@@H](NC(=O)OC(C)(C)C)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ CTSK P43235 4/20 0.61
▸ CTSS P25774 3/20 0.61
▸ CA2 P00918 2/20 0.53
▸ CA1 P00915 1/20 0.53
▸ CA7 P43166 1/20 0.53
▸ PREP P48147 1/20 0.49
▸ TRPA1 O75762 2/20 0.48
▸ CTSL P07711 2/20 0.48
▸ CTSB P07858 2/20 0.48
▸ CYP2D6 P10635 1/20 0.47
▸ TSHR P16473 2/20 0.45
▸ APP P05067 1/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ SDCBP O00560 1/20 0.43
▸ SDC2 P34741 1/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ GAA P10253 1/20 0.43
▸ ALOX15 P16050 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29674710 1.00 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL59323 1.00 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL467994 1.00 CTSK (0.61) CTSKCTSSCA2CA1CA7
SCHEMBL28058549 0.98 CTSK (0.59) CTSKCTSSCA2CA1CA7
Ammonia Solution, Strong SCHEMBL28313812 0.98 CTSK (0.59) CTSKCTSSCA2CA1CA7
Fluoride SCHEMBL7360444 0.98 CTSK (0.59) CTSKCTSSCA2CA1CA7
Fluoride SCHEMBL7360449 0.98 CTSK (0.59) CTSKCTSSCA2CA1CA7
SCHEMBL22371979 0.93 CTSK (0.63) CTSKCTSSCA2CA1CA7
SCHEMBL7345607 0.93 CTSK (0.63) CTSKCTSSCA2CA1CA7
SCHEMBL22371977 0.93 CTSK (0.63) CTSKCTSSCA2CA1CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025019172-A1 ANTIMICROBIAL EXTRACTANT FORMED FROM COPPER-CONTAINING SOURCE CORNING INCORPORATED (US) 2025-01-23 — — WO claimed
CN-114907231-B Indene chiral spiro fluorescent compound, and preparation method and application thereof 杭州师范大学 2024-02-23 — — CN claimed
WO-2024017221-A1 SYNTHESIS METHOD FOR α-AZIDO KETONE CONTAINING TERTIARY STEREOCENTER 常州大学 2024-01-25 — — WO claimed
CN-112321627-B Axis chiral arylethynyl silane compound and preparation method thereof 杭州师范大学 2023-09-01 — — CN claimed
CN-115108937-B Synthesis method of alpha-azido ketone containing three-level stereo center 常州大学 2023-08-22 — — CN claimed
CN-115108937-A Synthesis method of alpha-azidoketone containing three-level stereocenter 常州大学 2022-09-27 — — CN claimed
CN-114907231-A Indene chiral spiro fluorescent compound and preparation method and application thereof 杭州师范大学 2022-08-16 — — CN claimed
CN-114478627-A Allylation monophosphine ligand and preparation method thereof 湖北大学 2022-05-13 — — CN claimed
EP-3988538-A1 MODIFIED HYDROPHOBIC AUXILIARY MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF Zhejiang Zhida Pharmaceutical Co., Ltd. (CN) 2022-04-27 — — EP claimed
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF ZHEJIANG ZHIDA PHARMACEUTICAL CO., LTD. (CN) 2022-04-14 — — US claimed
US-20100290951-A1 SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER WORCESTER POLYTECHNIC INSITUTE (US) 2010-11-18 — — US claimed
WO-2010103486-A1 PYRAZOLO[1,5-A]-1,3,5-TRIAZINE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2010-09-16 — — WO claimed
EP-1794172-B1 ANTIVIRAL 4'-AZIDO-NUCLEOSIDES HOFFMANN LA ROCHE (CH) 2009-07-15 — — EP claimed
US-7265140-B2 Acyloxymethylcarbamate prodrugs of oxazolidinones PFIZER INC (US) 2007-09-04 — — US claimed
EP-1794172-A1 ANTIVIRAL 4'-AZIDO-NUCLEOSIDES F.HOFFMANN-LA ROCHE AG (CH) 2007-06-13 — — EP claimed
EP-1668005-B1 ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES PHARMACIA & UPJOHN CO LLC (US) 2007-02-14 — — EP claimed
EP-1668005-A1 ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES Pharmacia & Upjohn Company LLC (US) 2006-06-14 — — EP claimed
WO-2006021341-A1 ANTIVIRAL 4’-AZIDO-NUCLEOSIDES F. HOFFMANN-LA ROCHE AG (CH) 2006-03-02 — — WO claimed
US-20050267104-A1 E.g., ({[Acetyl({(5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran4-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}-methyl)amino]carbonyl}oxymethyl acetate; these compounds have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria PHARMACIA & UPJOHN COMPANY LLC 2005-12-01 — — US claimed
WO-2005028473-A1 ACYLOXYMETHYLCARBAMATE PRODRUGS OF OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY LLC (US) 2005-03-31 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050267104-A1 E.g., ({[Acetyl({(5R)-3-[4-(1,1-dioxidotetrahydro-2H-thiopyran4-yl)-3-fluorophenyl]-2-oxo-1,3-oxazolidin-5-yl}-methyl)amino]carbonyl}oxymethyl acetate; these compounds have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria HDAC3, HDAC1, OGA CTSK 1988/4885CTSS 3028/4885CA2 1189/4885
US-20100290951-A1 SURFACE-BASED AMMONIUM ION SENSOR: AN ELECTRODE DERIVATIZED WITH A SELF-ASSEMBLED MONOLAYER DNMT3A, ACMSD, CD4 CTSK 4373/4885CTSS 4833/4885CA2 114/4885
US-20220111055-A1 MODIFIED HYDROPHOBIC EXCIPIENT AND PREPARATION METHOD THEREOF CETP, SLC43A1, SLC27A1 CTSK 4188/4885CTSS 3839/4885CA2 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.