Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | ASAH1 | Q13510 | 7/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PDE6D | O43924 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28073618 | 0.94 | TSHR (0.67) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL5570257 | 0.87 | TSHR (0.67) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL6926893 | 0.80 | TSHR (0.79) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL205803 | 0.80 | TSHR (0.87) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL203352 | 0.75 | TSHR (0.70) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL203353 | 0.74 | TSHR (0.69) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| Benomyl SCHEMBL29379464 | 0.74 | TSHR (1.00) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| Benomyl SCHEMBL8379451 | 0.74 | TSHR (1.00) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| Benomyl SCHEMBL15681 | 0.74 | TSHR (1.00) | TSHRALDH1A1ASAH1MEN1KMT2A | |
| SCHEMBL28314135 | 0.74 | ALDH1A1 (0.47) | TSHRALDH1A1ASAH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110177847-A | Lotion, the composition comprising lotion, the film and associated method formed with it | 美国陶氏有机硅公司 | 2019-08-27 | — | — | CN | disclosed |